Elucidation of the biosynthetic pathway of B-group vitamins via genome mining of food-derived \(\textit{Bacillus velezensis}\) VTX20

B-vitamins are micronutrients that play an important role in various cellular processes of organisms, which only synthesized by plants, yeasts, and bacteria. Since animals humans lack the ability to synthesize B-vitamins, supplements vitamins from dietary B-vitamin producing bacteria required. In this study, we, for first time, shed some light on biosynthetic pathways involved folate (vitamin B9), riboflavin B2), biotin B7) production Bacillus velezensis VTX20. The genome-wide comparison revealed B. VTX20 shared high similarities with tequilensis KCTC 13622, subtilis 168, amyloliquefaciens DSM 7. Genomic analysis presence a complete biosynthesis pathway core components were not found most species. Moreover, strain also had metabolic probiotic traits. These results highlighted is producer can be applied further agricultural biotechnology industry.